What is Estrone? Estrone (E1) is one of the three major estrogens, alongside estradiol (E2) and estriol (E3), and is a steroid hormone primarily produced in the ovaries, adipose tissue, and adrenal glands. It is less potent than estradiol but plays a significant role in reproductive health, bone metabolism, and hormonal balance, particularly in postmenopausal women where it becomes the dominant estrogen. Measuring estrone levels in the blood is important for evaluating menopausal status, hormonal disorders, and certain cancers, such as breast or endometrial cancer.
Definition: The Estrone Unit Converter converts estrone concentrations between various units, enabling standardization of laboratory results for clinical use.
Purpose: It assists clinicians and researchers in interpreting estrone levels across different measurement units (e.g., pmol/L to pg/mL), ensuring accurate diagnosis and monitoring of hormonal and reproductive conditions.
Converting estrone concentrations between units is critical for:
Elevated Levels: High estrone levels may indicate conditions such as postmenopausal estrogen production in adipose tissue, hormone-producing tumors (e.g., ovarian or adrenal tumors), or excessive hormone replacement therapy. Elevated estrone is also a risk factor for estrogen-sensitive cancers, such as breast or endometrial cancer.
Low Levels: Low estrone levels are associated with menopause, ovarian failure, or hypogonadism. In premenopausal women, low levels may suggest anovulation or pituitary dysfunction.
Normal Ranges:
Interferences:
Q: Why are there different units for estrone?
A: Different units reflect varying standards; pmol/L is the SI unit, while pg/mL and ng/dL are commonly used in clinical practice, particularly in certain regions.
Q: What is a normal estrone level?
A: Normal estrone levels vary by sex and menopausal status (e.g., 7–40 pg/mL or 26–148 pmol/L for postmenopausal women). Consult a healthcare provider for interpretation.
Q: Can this converter be used for other hormones?
A: No, this converter is specific to estrone; other hormones (e.g., estradiol, estriol) have different molecular weights and conversion factors—consult a healthcare provider for accuracy.