1. What is Bilirubin?

Bilirubin is a yellow pigment formed during the normal breakdown of red blood cells. It is processed by the liver and excreted in bile. Elevated bilirubin levels can indicate liver dysfunction or hemolytic disorders.

2. How Does the Calculator Work?

The calculator uses the conversion formula:

Where:

• \( mg/dL \) — Bilirubin concentration in milligrams per deciliter
• \( \mu mol/L \) — Bilirubin concentration in micromoles per liter
• \( 0.58466 \) — Conversion factor

Explanation: This formula converts bilirubin values from mg/dL (commonly used in the US) to μmol/L (international standard units).

3. Importance of Bilirubin Measurement

Details: Bilirubin measurement is crucial for assessing liver function, diagnosing jaundice, monitoring liver diseases, and evaluating hemolytic conditions.

4. Using the Calculator

Tips: Enter bilirubin value in mg/dL. The calculator will automatically convert it to μmol/L. Values must be non-negative.

5. Frequently Asked Questions (FAQ)

Q1: Why convert between mg/dL and μmol/L?
A: Different countries and medical institutions use different units. Conversion ensures consistent interpretation of results across different measurement systems.

Q2: What are normal bilirubin levels?
A: Normal total bilirubin is typically 0.1-1.0 mg/dL (1.7-17.1 μmol/L). Levels above this range may indicate liver problems or hemolysis.

Q3: What's the difference between direct and indirect bilirubin?
A: Indirect (unconjugated) bilirubin is the initial breakdown product, while direct (conjugated) bilirubin has been processed by the liver. The distinction helps diagnose the cause of jaundice.

Q4: When should bilirubin be measured?
A: Bilirubin testing is indicated when jaundice is present, to monitor liver disease, assess neonatal jaundice, or evaluate suspected hemolytic disorders.

Q5: Are there limitations to bilirubin measurement?
A: Bilirubin levels can be affected by fasting, hemolysis of the sample, and certain medications. Always interpret results in clinical context.