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Protein Molar Weight Formula:
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Protein molar weight refers to the molecular weight of a protein molecule, typically expressed in grams per mole (g/mol). It's calculated based on the number of amino acids and their average molecular weight.
The calculator uses the protein molar weight formula:
Where:
Explanation: This calculation provides an approximate molecular weight as it uses an average value for all amino acids rather than accounting for the specific composition.
Details: Knowing a protein's molar weight is essential for various biochemical applications including protein quantification, electrophoresis, chromatography, and determining concentration for experimental procedures.
Tips: Enter the number of amino acids in your protein and the average amino acid molecular weight (default is 110 g/mol). For more accurate results, use the specific molecular weight based on your protein's amino acid composition.
Q1: Why is 110 g/mol used as the average amino acid molecular weight?
A: 110 g/mol is a commonly accepted average that accounts for the varying sizes and molecular weights of the 20 standard amino acids found in proteins.
Q2: How accurate is this estimation method?
A: This method provides a reasonable approximation but may vary by 5-15% from the actual molecular weight depending on the specific amino acid composition of the protein.
Q3: When would I need a more precise calculation?
A: For exact molecular weight determination, especially in research applications, you would need to calculate based on the exact amino acid sequence of your protein.
Q4: Does this account for post-translational modifications?
A: No, this calculation only considers the amino acid backbone. Post-translational modifications like phosphorylation or glycosylation will add additional molecular weight.
Q5: Can I use this for peptide calculations?
A: Yes, this formula works for both proteins and peptides. Simply enter the number of amino acids in your peptide chain.